Bhavya Ravi, PhD

Postdoctoral Fellow

bhavya lab website pic.jpg

Education and Training:

  • Undergraduate

    • BE, Birla Institute of Technology and Science, India

      • Chemical Engineering​

  • Doctoral/graduate​

    • MS, Birla Institute of Technology and Science, India

      • Biological Sciences ​

    • PhD, University of Miami Miller School of Medicine, Miami, FL

      • Neuroscience​

      • Lab of Kevin Collins​

  • Subsequent position​​

    • Medical Writer at a contract research organization based in Bethesda​

Research Interests:

Establishing an iPS cell-derived co-culture model for SMA, understanding the molecular basis of level motor neuron vulnerability and loss in SMA using single nuclear sequencing

Current Projects:

  1. Alternative exon usage in Slit 2 in SMA;

  2. Generating and characterizing an iPS cell derived co-culture model of SMA;

  3. Using single-cell and single-nuclear sequencing to characterize the molecular basis of selective motor neuron loss in SMA

Selected Publications:

  • Richard Kopchock III, Bhavya Ravi, and Kevin M Collins. The sex-specific, cholinergic VC motor neurons are involved in both locomotion and egg-laying behavior in C. elegans. (In preparation).

  • Bhavya Ravi, Jian Zhao, Sana Chaudhry, Mattingly Bartole, Christian Guijarro, Lijun Kang, and Kevin M Collins (2019). Presynaptic Gαo (GOA-1) signaling depresses command neuron excitability to allow for stretch-dependent modulation of egg-laying behavior in C. elegans. (In review) Preprint: https://www.biorxiv.org/content/10.1101/701664v1

  • Bhavya Ravi, Anthony Antonellis, Charlotte J Sumner, and Andrew P Lieberman (2019). Genetic approaches to the treatment of inherited neuromuscular diseases. Human Molecular genetics https://doi.org/10.1093/hmg/ddz131. PMID: 31227866

  • Bhavya Ravi, Jessica Garcia, and Kevin M Collins (2018). Homeostatic feedback modulates the development of two-state patterned activity in a model serotonin motor circuit in Caenorhabditis elegans. Journal of Neuroscience; 38(28): 6283-6298. PMID: 29891728.

  • Bhavya Ravi#, Layla Nassar#, Richard Kopchock III#, Pravat Dhakal#, Michael Scheetz, and Kevin M Collins (2018). Ratiometric calcium imaging of individual neurons in behaving Caenorhabditis elegans. Journal of Visualized Experiments; (132): e56911. (#equal contribution). PMID: 29443112.

Contact:

bravi1@jhmi.edu