Brett McCray, MD PhD

Assistant Professor 

Current Appointments: 

  • Assistant Professor, Department of Neurology 

    • Johns Hopkins University, Baltimore, Maryland

Education and Training:

  • Undergraduate

    • BS, DukeUniversity, Durham, NC

      • Psychology

  • Doctoral/graduate​

    • MD, University of Pennsylvania School of Medicine, Philadelphia, PA​​

    • PhD, University of Pennsylvania School of Medicine, Philadelphia, PA​​

      • Neuroscience​

      • Lab of J. Paul Taylor

  • Postdoctoral​

    • Intern, Internal Medicine, Brigham & Women's Hospital, Boston, MA

    • Resident, Neurology, Massachusetts General Hospital, Boston, MA

    • Fellowship, Neuromuscular Disease, Johns Hopkins University School of Medicine, Baltimore, MD

Research Interests:

Inherited neuropathy, peripheral neuropathy, Charcot Marie Tooth disease, TRPV4, axonal transport

Selected Publications:

  • Roda RH, McCray BA, Klein CJ, Hoke A. Novel hemizygous nonsense mutation in DRP2 is associated with inherited neuropathy. Neurol Genet. 2018 Feb;4(1):e220. PubMed PMID: 29473052; PubMed Central PMCID: PMC5820600.

  • McCray BA, Hurst W, Crawford TO, Lloyd TE. Fifteen-year longitudinal follow-up of a patient with severe early-onset Charcot-Marie-Tooth disease type 2A. Muscle Nerve 2017 Dec 20;PubMed PMID: 29266326.

  • McCray BA, Skordalakes E, Taylor JP. Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation. Hum Mol Genet. 2010 Mar 15;19(6):1033-47. PubMed PMID: 20028791; PubMed Central PMCID: PMC2830827.

  • McCray BA, Taylor JP. The role of autophagy in age-related neurodegeneration. Neurosignals 2008;16(1):75-84. PubMed PMID: 18097162.

  • Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, Nedelsky NB, Schwartz SL, DiProspero NA, Knight MA, Schuldiner O, Padmanabhan R, Hild M, Berry DL, Garza D, Hubbert CC, Yao TP, Baehrecke EH, Taylor JP. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 2007 Jun 14;447(7146):859-63. PubMed PMID: 17568747.

Contact:

bmccray3@jhmi.edu