Daniel Ramos, PhD
Postdoctoral Fellow
Education and Training:
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Undergraduate
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BS, University of Pennsylvania, Neuroscience
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2009-2013​
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Graduate​​
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PhD, Johns Hopkins University​, Neuroscience
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2013-2019​
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Previous Positions
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Undergraduate researcher: University of Pennsylvania
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Lab of Dr. Wenqin Luo
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Undergraduate researcher: University of Pennsylvania
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Lab of Dr. Aaron Gitler
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Undergraduate researcher: Massachusetts Institute of Technology
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Lab of Dr. Matthew Wilson
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Subsequent Position​​
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Postdoctoral fellow with ​Michael Ward as part of the iNDI (iPSC Neurodegeneration Initiative) team
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Current Projects:
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Understanding the role of SMN-AS1 in SMN gene expression and potential as a novel SMA therapeutic
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Elucidating age-dependent SMN expression in SMA disease-relevant human tissues and implications for SMA treatment
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Selected Publications:
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Ramos DM, d'Ydewalle C, Gabbeta V, Dakka A, Klein SK, Norris DA., . . . Sumner, CJ (2019). Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. J Clin Invest, 129(11), 4817-4831. doi:10.1172/JCI124120. PMID: 31589162
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Auslander N*, Ramos DM*, Zelaya I, Karathia H, Schäffer AA, Crawford TO, Sumner CJ, Ruppin E. The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases (*co-first authors). In review at Cell Systems.
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d'Ydewalle C, Ramos DM, Pyles NJ, Ng SY, Gorz M, Pilato CM, Ling K, Kong L, Ward AJ, Rubin LL, Rigo F, Bennett CF, Sumner CJ. The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy. Neuron. 2017 Jan 4. pii: S0896-6273(16)30901-1. PMID: 28017471
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Contact:
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