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Daniel Ramos, PhD

Postdoctoral Fellow


Education and Training:

  • Undergraduate

    • BS, University of Pennsylvania, Neuroscience

      • 2009-2013​

  • Graduate​​

    • PhD, Johns Hopkins University​, Neuroscience

      • 2013-2019​

  • Previous Positions

    • Undergraduate researcher: University of Pennsylvania

      • Lab of Dr. Wenqin Luo 

    • Undergraduate researcher: University of Pennsylvania

      • Lab of Dr. Aaron Gitler

    • Undergraduate researcher: Massachusetts Institute of Technology 

      • Lab of Dr. Matthew Wilson 

  • Subsequent Position​​

    • Postdoctoral fellow with ​Michael Ward as part of the iNDI (iPSC Neurodegeneration Initiative) team

Current Projects:

  • Understanding the role of SMN-AS1 in SMN gene expression and potential as a novel SMA therapeutic 

  • Elucidating age-dependent SMN expression in SMA disease-relevant human tissues and implications for SMA treatment

Selected Publications:

  1. Ramos DM, d'Ydewalle C, Gabbeta V, Dakka A, Klein SK, Norris DA., . . . Sumner, CJ (2019). Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. J Clin Invest, 129(11), 4817-4831. doi:10.1172/JCI124120. PMID: 31589162

  2. Auslander N*, Ramos DM*, Zelaya I, Karathia H, Schäffer AA, Crawford TO, Sumner CJ, Ruppin E. The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases (*co-first authors). In review at Cell Systems.

  3. d'Ydewalle C, Ramos DM, Pyles NJ, Ng SY, Gorz M, Pilato CM, Ling K, Kong L, Ward AJ, Rubin LL, Rigo F, Bennett CF, Sumner CJ. The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy. Neuron. 2017 Jan 4. pii: S0896-6273(16)30901-1. PMID: 28017471


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