Sumner Lab

Research Interests:

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Neurodegeneration, spinal muscular atrophy, reproductive health care for incarcerated women (I am an ARRWIP Research Associate: https://www.arrwip.org/arrwip-team), neuronal regeneration and the retina (which I studied in Dr. Seth Blackshaw's lab: https://blackshawlab.com/lab-members/)

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Current Project:

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​I am currently assessing evidence of developmental arrest as well as evidence of ongoing degeneration in human autopsy tissues of SMA patients treated with nusinersen. Our goal is to determine the cellular benefits of nusinersen, which was the first FDA-approved drug to treat SMA patients.

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Publications:

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• "Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas", accepted in Science in Sept 2020 

  • https://www.biorxiv.org/content/10.1101/717876v3

• "The Compendium of U.S. Jails: Creating and Conducting Research with the First Comprehensive Contact Database of U.S. Jails", submitted and under-review

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Contact:

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tparayi1@jhu.edu